Endocrine Abstracts

Introduction: Endocrinopathies are rare causes of erectile dysfunction and previously cases of hyperprolactinaemia and pituitary adenomas have been reported.Case report: We present the clinical case of a 27-year old male, married for 4 years with no children, presented with possible infertility and erectile dysfunction which was previously interpreted as caused by a poor social and psychological situation in the family. After additional endocrinological ...

Objectives: This study aimed to assess the ability of aldosterone in saline infusion test (SIT) to predict biochemical remission of primary aldosteronism.Methods: We retrospectively analysed 42 patients (19 (45%) females, mean age 49±12 years) with primary aldosteronism who underwent adrenalectomy (after adrenal vein sampling confirmation of unilateral disease) from 2017 to 2022. Aldosterone in SIT was determined on the fifth postoperative day, as wel...

Background: Adrenal venous sampling (AVS) is considered the gold standard for differentiating an aldosterone- producing adenoma (aPA) from bilateral adrenal hyperplasia (BAH)Objective: The aim of this study is to present our experience with this method in our hospital.Methods: We performed a retrospective analysis of 105 patients who underwent the AVS protocol at our centre between 2015 and 2022 for PA.Result...

Background: Adrenal venous sampling (AVS) is the gold standard to differentiate patients with unilateral primary aldosteronism (UPA) from those with bilateral disease (BPA). As this is an invasive method, there are a lot of different scoring systems developed for primary aldosteronism (PA) subtyping. Integer scoring system is one of those established for BPA subtyping.Objective: The aim of this study was to evaluate the efficiency of using the online Int...

Background: Although adrenal vein sampling (AVS) is a technically demanding procedure, it is still considered the gold standard for subtyping primary aldosteronism (PA). The aim of the study was to analyze the success rate of AVS in patients with PA.Methods: In all patients AVS was performed sequentially during continuous stimulation with adrenocorticotrophic hormone by one interventional radiologist. Adrenal vein cannulation was considered successful if...

Background: Pituitary apoplexy is a rare complication of pituitary adenomas, especially nonfunctioning tumors. It is associated with severe headache, which may be accompanied by visual disturbances or ocular palsy. Here we present two patients who suffered from pituitary adenoma apoplexy while receiving anticoagulation therapy with non-vitamin K antagonists.Case presentation: A 74-year old woman was diagnosed with a non-functioning pituitary macroadenoma...

Empty sella is characterized by the radiological appearance of an enlarged or deformed sella turcica which is completely or partially filled with cerebrospinal fluid resulting in a displacement of the normal pituitary gland. Primary empty sella (PES) refers to the empty sella appearance of unknown etiology, diagnosed after excluding a history of previous pituitary pathology. The prevalence of hypopituitarism in empty sella syndrome varies between 2 and 32% in different publish...

Background: The existing consensus for patients with primary aldosteronism (PA) after unilateral adrenalectomy recommends annual follow-up to rule out persistence or recurrence of the disease.Objectives: The aim of the study was to assess the remission rate in patients with PA ≥1 year after adrenalectomy.Methods: Of the 41 patients who underwent adrenalectomy for PA between 2016 and 2021, 24 had available follow-up data and w...

Introduction: Adrenal vein sampling (AVS) is a gold standard in the assessment of the cause of primary aldosteronism (PA). It is technically demanding procedure having the high rate of failure, even in expert centres. Our study aimed to investigatewhether the data on aldosterone and cortisol concentration from successfully cannulated adrenal vein could determine the subtype of PA in certain patients with partially successful AVS.Materials and methods: Th...

Introduction: Adrenal vein sampling (AVS) represents the gold standard in the identification of the source of aldosterone hypersecretion in patients with primary aldosteronism (PA). It is a technically demanding procedure and, in some cases, only one adrenal vein is successfully cannulated. Our study aimed to examine the aldosterone/cortisol ratio between the peripheral and adrenal veins in order to determine peripheral/adrenal vein aldosterone/cortisol ratio cut-off value tha...